Active efflux mechanisms for antimicrobial resistance
نویسندگان
چکیده
منابع مشابه
Efflux-mediated antimicrobial resistance.
Antibiotic resistance continues to plague antimicrobial chemotherapy of infectious disease. And while true biocide resistance is as yet unrealized, in vitro and in vivo episodes of reduced biocide susceptibility are common and the history of antibiotic resistance should not be ignored in the development and use of biocidal agents. Efflux mechanisms of resistance, both drug specific and multidru...
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There is no doubt that antimicrobial agents have saved the human race from a lot of suffering due to infectious disease burden. Without antimicrobial agents, millions of people would have succumbed to infectious diseases. Man has survived the accidental wrath of microorganisms using antimicrobial agents and other mechanisms that keep them at bay. Hardly years after the discovery and use of the ...
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Campylobacter jejuni and Campylobacter coli are recognized as the most common causative agents of bacterial gastroenteritis in the world. Humans most often become infected by ingesting contaminated food, especially undercooked chicken, but also other sources of bacteria have been described. Campylobacteriosis is normally a self-limiting disease. Antimicrobial treatment is needed only in patient...
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In the last 50 years bacteria have demonstrated a remarkable ability to develop and share resistance to every antibiotic that has been developed, often by quite unexpected mechanisms and much more readily than was originally predicted (Spratt, 1994). Antibiotic resistant bacteria can live and multiply in the presence of therapeutic levels of antibiotics. They can be resistant in their natural s...
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OBJECTIVES To determine the prevalence of expression and function(s) of Bacteroides fragilis RND family efflux transport systems (bmeABC1-16). METHODS The mRNA transcripts of bmeB efflux pump genes were detected in a wild-type strain ADB77 by RT-PCR and expression in different strains was quantified by comparative quantitative real-time RT-PCR. In order to determine independent or additive fu...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1992
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.36.4.695